Non-descanned second harmonic imaging

Recordings of simultaneous, non-descanned forward second harmonic generation (SHG) and non-descanned backward 2PE autofluorescence in label-free mouse enthesis organs. Collagen fibers of the Achilles tendon were subsequently analyzed using CT-FIRE.

As published in:

Van Mechelen et al., Impact of barrier tissue inflammation and physical activity on joint homeostasis in mice, Rheumatology, Volume 61, Issue 4, April 2022, Pages 1690–1698, https://doi.org/10.1093/rheumatology/keab517